DISCOVERING
novel therapeutics
against enzymes that contribute to the dysregulation
of RNA and DNA processes in serious diseases
Coordinated regulation of RNA and DNA
processes are required for maintaining cellular health
Various RNA and DNA processing and signaling mechanisms contribute to maintaining cellular homeostasis, including metabolism, differentiation, and responses to external stimuli.
There is growing biological understanding around various enzymes involved in these mechanisms and how their dysregulation contributes to serious diseases such as cancer and autoimmune diseases.
Targeting RNA and DNA-processing
and signaling enzymes in disease represents a
unique opportunity for
developing novel therapeutics.